Calexico is a city in Imperial County, California. The population was 38,572 at the 2010 census, up from 27,109 at the 2000 census. Calexico is about 122mi east of San Diego and 62mi west of Yuma, Arizona. The name of the city is a portmanteau of California and Mexico, which, like that of its adjacent sister city of Mexicali, emphasizes its identity as a border city.Major events every year are the Mariachi festival on March 25 followed by the SDSU "Perspective of the Latino Race" art exhibition on April 3.GeographyAccording to the United States Census Bureau, at the 2010 census, the city had a total area of 6.2sqmi, all land. Calexico is located 230mi southeast of Los Angeles, 125mi east of San Diego, 260mi west of Phoenix, and adjacent to Mexicali, Baja California, Mexico.Calexico's location provides easy overnight trucking access to all those transportation hubs plus the ports of Long Beach, California, and Ensenada, Baja California, Mexico.